In the pursuit of higher biological activity and superior therapeutic effects in vaccines and biopharmaceuticals, every aspect of the production process is critical. Particularly in key processes like cell culture and vaccine preparation, large-scale liquid/solid mixing directly impacts final product quality and yield.
Redefining Biopharmaceutical Mixing Standards
The BioMixer 200/1000 CWA series represents a significant advancement in mixing technology specifically designed for vaccine production and regenerative medicine applications. This system establishes new benchmarks for large-scale liquid/solid mixing through exceptional efficiency, rigorous contamination control, and user-friendly operation.
Key Advantages for Biopharmaceutical Production
1. Unmatched Mixing Efficiency: The series employs advanced mixing technology enabling rapid, uniform blending of solids and liquids. Whether preparing cell culture media or dispersing vaccine components, the system significantly reduces processing time while improving product consistency.
2. Stringent Contamination Control: The innovative single-use mixing bag design eliminates cross-contamination risks while simplifying cleaning validation. This approach ensures sterile mixing conditions for sensitive biological materials.
3. Intuitive Operation: Featuring a touchscreen interface with clear parameter visualization, the system reduces training requirements while improving operational efficiency.
4. Advanced Process Control: Beyond standard temperature regulation, optional modules enable real-time pH and dissolved oxygen monitoring and adjustment, allowing optimization of biological growth conditions.
5. Comprehensive Data Integration: Compatibility with manufacturing execution systems (MES) and laboratory information management systems (LIMS) supports full process traceability and regulatory compliance.
Technical Specifications
| Model |
CWA200 |
CWA1000 |
| Capacity |
200L |
1000L |
| Temperature Range |
2-45°C (±0.1°C) |
2-45°C (±0.1°C) |
| Mixing Speed |
10-200 rpm (±1 rpm) |
10-200 rpm (±1 rpm) |
| Dimensions |
1190×982×1188 mm |
1540×1280×1630 mm |
| Weight |
~200kg (empty) |
~500kg (empty) |
Single-Use Mixing Bags
The system utilizes specialized 3D mixing bags designed for optimal solid-liquid blending. These disposable components feature:
- High-torque mixing structures for effective particle dispersion
- Domestic manufacturing ensuring supply chain stability
- Customizable configurations for specific process requirements
The integration of advanced mixing technology with single-use systems addresses critical challenges in biopharmaceutical production, offering solutions for contamination control, process efficiency, and regulatory compliance.
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